"ligamentum_flavum.csv" contains all data to reproduce reported data Variable Names: Short Description ges: sex, maennlich = male, weiblich = female diag01-diag03: diagnosis 01 - 03, Osteochondrose = osteochondrosis, Gefuegestoerung = structural instability, Skoliose = scoliosis er: estrogen receptor, quantitative as IRS (product score, values 0-12) sairyo_fibr_abs: fibrosis according to Sairyo, quantitative (percentage of total area) sairyo_fibr_score: fibrosis score according to Sairyo, quantitative (0-4) sairyo_elast_abs: loss of elastic fibers according to Sairyo, quantitative (percentage of total area) sairyo_elast_score: score of loss of elastic fibers according to Sairyo, quantitative (0-4) okuda_deg: degeneration of elastic fibers according to Okuda, mild = mild, moderate = moderate, schwer = severe okuda_prolif: proliferation of elastic fibers according to Okuda, mild = mild, moderate = moderate, schwer = severe okuda_elast: loss of elastic fibers according to Okuda, mild = mild, moderate = moderate, schwer = severe alter: age, in years BSV_Kontrollgruppe: control group, yes = control group, no = patient group Osteochondrose: diagnosis of osteochondrosis, yes = osteochondrosis reported, no = osteochondrosis not reported SKS: diagnosis of spinal stenosis, yes = spinal stenosis reported, no = spinal stenosis not reported Skoliose: diagnosis of scoliosis, yes = scoliosis reported, no = scoliosis not reported Kontr_vs_Pat: patient or control group, Patient = patient, Kontrolle = control group er_dich: estrogen receptor dichotomized, IRS <= 1 = negative, IRS <= 2 positive okuda_deg_score: degeneration of elastic fibers according to Okuda, 1 = mild, 2 = moderate, 3 = severe okuda_prolif_score: proliferation of elastic fibers according to Okuda, 1 = mild, 2 = moderate, 3 = severe okuda_elast_score: loss of elastic fibers according to Okuda, 1 = mild, 2 = moderate, 3 = severe contr_vs_pat: patient or control group, patient = patient group, control = control group sex: sex, male, female Sairyo: Sairyo, K.; Biyani, A.; Goel, V.; Leaman, D.; Booth, R.J.R.; Thomas, J.; Gehling, D.; Vishnubhotla, S.L.; Long, R.; Ebraheim, N. Pathomechanism of ligamentum flavum hypertrophy: A multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments. Spine 2005, 30, 2649-2656. Okuda: Okuda, T.; Baba, I.; Fujimoto, Y.; Tanaka, N.; Sumida, T.; Manabe, H.; Hayashi, Y.; Ochi, M. The Pathology of Ligamentum Flavum in Degenerative Lumbar Disease. Spine 2004, 29, 1689-1697. https://doi.org/10.1097/01.BRS.0000132510.25378.8C.